Nicolas Moitessier
Maitrise - Université Nancy I, France
Ph.D. - Université Nancy I, France
Postdoctoral Fellow - Université de Montréal, Canada
Chargé de Recherche - CNRS, Nancy, France
Assistant Professor - McGill University, Canada
Associate Professor - McGill University, Canada
Full Professor - McGill University, Canada
Co-Founder and CSO - Molecular Forecaster
Associate Editor - Eur. J. Med. Chem.
Biography
He received his undergraduate training and his Ph.D (1998) from Université Henri Poincaré-Nancy I (France) under the guidance of Dr. Yves Chapleur (carbohydrate chemistry) working in close collaboration with a theoretical chemistry group (Dr. Maigret). His PhD was followed by post-doctoral studies with Prof. Shephen Hanessian (1998-2000, medicinal chemistry, asymmetric synthesis).
In 2001, he moved back to Nancy to start an academic career (Chargé de Recherche, CNRS) then back to Montréal in 2003 (Assistant Professor, McGill University). In 2009, he was promoted to Associate Professor and in 2019 he was promoted to Full Professor.
Research Interests
Design, synthesis and evaluation of potential drugs with a focus on Alzheimer's disease and cancer.
Development of novel methodologies for the synthesis of chiral cyclic and bicyclic scaffolds.
Design, synthesis and evaluation of asymmetric catalysts.
Development of a fully integrated computer-aided drug design platform Forecaster and computational catalyst/biocatalyst platform Virtual Chemist.
Development of a novel molecular mechanics method - H-TEQ.
Development of computational tools for reactive metabolite predictions Impacts, for drug-drug interactions and covalent drug binding.